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NDT Plus Advance Access published online on September 1, 2008
NDT Plus, doi:10.1093/ndtplus/sfn142
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

How much is red blood cell fragmentation increased by the use of closed luer lock access devices on catheter hubs?

Sunny Eloot1, Jean-Yves De Vos2 and Remi Hombrouckx2

1 Nephrology Section, Ghent University Hospital, Ghent
2 Nephrology Section, AZ Werken Glorieux, Ronse, Belgium

Correspondence: Sunny Eloot, Nephrology Department-Dialysis Unit, Ghent University Hospital 1P8, De Pintelaan 185, 9000 Gent, Belgium. Tel: +32-9-332-10-25; Fax: +32-9-332-45-61; E-mail: sunny.eloot@ugent.be

Key Words: catheter • haemodialysis • haemolysis • infection

Received for publication April 24, 2008. Accepted for publication August 7, 2008.

The first 10% of the full text of this article appears below.


   Introduction
 
The opening and manipulation of central venous (CV) catheters before and after each dialysis event might result in catheter-related blood stream infections [1–3]. In order to reduce those infection risks, different types of closed luer lock access devices are commercially available.

Such connectors are placed on the arterial and venous catheter hub and are designed with a split septum of medical grade silicon such that they can stay safely in place during the interdialytic period as well as during dialysis.

Besides the proven microbiological efficacy in infection reduction and/or elimination [4–6], those types of connectors are designed to apply with blood flows up to 600 mL/min during dialysis and to create an unobstructed fluid path in the open position, . . . [Full Text of this Article]


   Patients and methods
 

   Results and discussion
 

   Conclusion
 

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