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NDT Plus 2009 2(2):143-146; doi:10.1093/ndtplus/sfn212
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© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Urinary tract obstruction due to extramedullary plasmacytoma: report of two cases

Naïke Bigé1, Bertrand Arnulf2, Aurelie Hummel1, Eric De Keyser3, Virginie Royal4, A. Buzyn5 and Fadi Fakhouri1

1 Nephrology Department, Université Paris Descartes, AP-HP, Necker Hospital
2 Haematology Department, Saint Louis Hospital
3 Radiology Department
4 Pathology Department
5 Haematology Department, Université Paris Descartes, AP-HP, Necker Hospital, Paris

Correspondence: Correspondence and offprint requests to: Fadi Fakhouri, Molecular Genetics and Rheumatology Section, Faculty of Medicine, Imperial College, Hammersmith Campus, London, UK. E-mail: fadi.fakhouri{at}nck.aphp.fr


  Abstract

Extramedullary plasmacytomas (EMP) rarely occur during the course of multiple myeloma (MM). Most frequent reported sites are superior respiratory airways, pleura, lung, lymph nodes, skin, subcutaneous and soft tissues, testicles and liver. EMP involving the urinary tract are very uncommon and have been ill-described in the literature. We report two unusual cases of obstructive urinary tract EMP revealing a relapse of MM after allogeneic stem cell transplantation. Clinicians must be aware that EMP may be responsible for urinary tract obstruction even in the absence of medullary progression of MM.

Key Words: bladder • multiple myeloma • plasmacytoma • urinary tract

Received for publication December 13, 2008. Accepted for publication December 23, 2008.


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