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NDT Plus 2008 1(Supplement 4):iv29-iv35; doi:10.1093/ndtplus/sfn121
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

This article appears in the following NDT Plus issue: Dialysis Initiatives May 2007, Berlin, Germany [View the issue table of contents]

Monitoring of the peritoneal membrane

Dirk G. Struijk

Dianet Foundation, Amsterdam, Utrecht, The Netherlands

Correspondence: Dirk G. Struijk, Department of Nephrology, A01-136, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 ED Amsterdam, The Netherlands. Tel: +31-205665990; Fax: +31-20-5669588; E-mail: D.G.Struijk{at}amc.nl


  Abstract

Background. Indirect methods can be used to provide valuable information about peritoneal structure and function for the indirect analysis of peritoneal membrane.

Methods. The focus of this paper will be on the commonly available tools for this purpose. First, the value and clinical relevance of CA125 as a marker of mesothelial cell mass in peritoneal effluent will be evaluated. Thereafter, monitoring the peritoneal membrane by using its properties to transport solutes and water will be discussed.

Results. The data obtained can be useful for tailoring dialysis adequacy, analysis of clinical problems such as ultrafiltration failure or to predict the development of peritoneal sclerosis.

Key Words: peritoneal membrane • peritoneal transport • peritoneal equilibrium test • fluid kinetics • CA125

Received for publication February 19, 2008. Accepted for publication July 1, 2008.


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