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NDT Plus 2008 1(Supplement 3):iii35-iii38; doi:10.1093/ndtplus/sfn085
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Current status of parathyroidectomy for secondary hyperparathyroidism in Japan

Yoshihiro Tominaga

Department of Transplant and Endocrine Surgery, Nagoya Second Red Cross Hospital, Nagoya, Japan

Correspondence: Yoshihiro Tominaga, 2-9 Myoken-cho Showa-ku, Nagoya 4668650, Japan. Tel: +81-52-832-1121; Fax: +81-52-832-0149; E-mail: ytomi@nagoya2.jrc.or.jp

Key Words: cinacalcet HCl • parathyroid hyperplasia • parathyroidectomy • percutaneous ethanol injection therapy • secondary hyperparathyroidism

Received for publication February 26, 2008. Accepted for publication February 29, 2008.

The first 150 words of the full text of this article appear below.


   Introduction
 
Hyperparathyroidism (HPT) is a common complication in haemodialysis patients, associated with morbidity and sometimes mortality [1]. In the majority of patients with secondary hyperparathyroidism (2HPT), this can be managed by medical treatment but this does not always give adequate control of the parathyroid disorder. Some patients require intervention treatment of the parathyroid glands including parathyroidectomy (PTx) and percutaneous ethanol injection therapy (PEIT). Successful surgical treatment achieves a dramatic drop of the parathyroid hormone (PTH) level, relieves the patient from clinical symptoms and reduces mortality [2].

Surgical indications in 2HPT and the frequency of PTx might be influenced by medical therapy, i.e. vitamin D and vitamin D analogues injection therapy, sevelamer hydrochloride, calcimimetics, etc., and the composition of the haemodialysis . . . [Full Text of this Article]


   Background and frequency of parathyroidectomy in Japan
 

   Surgical indications for 2HPT
 

   Surgical procedures
 

   Clinical improvement and survival rate
 

   Problems facing PTx
 

   Parathyroidectomy for secondary hyperparathyroidism in the calciminetic era
 

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