NDT Plus Advance Access originally published online on August 26, 2008
NDT Plus 2008 1(6):442-444; doi:10.1093/ndtplus/sfn139
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Secondary syphilis after renal transplantation
1 Divisions of Nephrology
2 Infectious Diseases
3 Gastroenterology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
Correspondence: Correspondence and offprint requests to: Nada Kanaan, Division of Nephrology, Cliniques Universitaires Saint Luc, 10 Av. Hippocrate, 1200 Brussel, Belgium. Tel: +32-2-7641855; Fax: +32-2-7642836; E-mail: nada.kanaan@uclouvain.be
Key Words: hepatitis syphilis transplantation
Received for publication July 28, 2008. Accepted for publication August 4, 2008.
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Potent immunosuppressive agents make renal transplant recipients at increased risk of infections. Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum with varied and often subtle clinical manifestations. If unrecognized, it can have devastating consequences [1]. The incidence of syphilis decreased significantly in the 1940s with the advent of penicillin, with later outbreaks being related to HIV infections, sexual practices and the use of drugs [2]. With the declining prevalence of syphilis, many physicians have become unfamiliar with its clinical presentation. We report a case of secondary syphilis in a renal transplant recipient who presented with systemic signs of illness and a mild hepatitis, in whom diagnosis was delayed until he developed a characteristic cutaneous rash.
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In June 2007, a 35-year-old man who had received
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