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NDT Plus Advance Access originally published online on May 21, 2008
NDT Plus 2008 1(5):310-312; doi:10.1093/ndtplus/sfn054
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Obstructive nephropathy and kidney injury associated with ketamine abuse

Nicholas M. Selby1, John Anderson1, Peter Bungay2, Lindsay J. Chesterton1 and Nitin V. Kolhe1

1 Department of Renal Medicine
2 Department of Interventional Radiology, Derby City Hospital, Derby, UK

Correspondence: Correspondence and offprint requests to: Nicholas M. Selby, Department of Renal Medicine, Derby City Hospital, Uttoxeter Road, Derby DE22 3NE, UK. Tel: +44-01332-340131; Fax: +44-01332-625975; E-mail: nick.selby@nhs.net

Key Words: acute renal failure • hydronephrosis • inflammatory cystitis • ketamine

Received for publication April 14, 2008. Accepted for publication April 18, 2008.

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    Case report
 
A 26-year-old man presented to the emergency department in a state of collapse. One month prior to the current admission he was seen by a urologist with frank haematuria associated with colicky abdominal pain, increased urinary frequency and dysuria. Although he was initially treated for a urinary tract infection a CT abdomen demonstrated moderate bilateral hydronephrosis. No cause for the hydronephrosis was seen, in particular no calculi. Common bile duct (CBD) was measured at 8 mm. Cystoscopy revealed a diffusely inflamed bladder with marked reduction in capacity (150 cc) but no obstruction at the ureteric orifices. The bladder biopsy showed inflammatory change but no dysplasia or malignancy. No firm diagnosis was reached and the patient was discharged with outpatient . . . [Full Text of this Article]


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