NDT Plus Advance Access originally published online on January 4, 2008
NDT Plus 2008 1(2):94-96; doi:10.1093/ndtplus/sfm032
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Pseudo-anion gap acidosis
1 Division of Nephrology, University of Rochester School of Medicine, Rochester, NY, USA
2 Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine, Rochester, NY, USA
Correspondence: Sankar D. Navaneethan, Department of Medicine, Nephrology Division, University of Rochester School of Medicine, Rochester, NY, USA. Tel: +1-585-319-6129; Fax: +1-585-442-9201; E-mail: Sankar_navaneethan@urmc.rochester.edu
Key Words: acidosis anion gap
Received for publication October 5, 2007. Accepted for publication November 30, 2007.
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A 74-year-old Caucasian male was referred to our clinic for low serum bicarbonate levels and a high anion gap (HAG). Past medical history included hypertension, hypothyroidism, iron deficiency anaemia secondary to gastrointestinal bleeding and hyperlipidaemia. He was on Bicitra 30 mL orally three times daily, levothyroxine 75 mcg daily, atorvastatin 10 mg daily, ferrous sulphate 324 mg daily and chlorthalidone 12.5 mg daily. He denied smoking, alcoholism or illegal drug abuse. Physical exam was unremarkable.
His laboratory values obtained over the 18 months after our evaluation are outlined in Table 1. Arterial blood gas showed a pH of 7.37, PCO2 of 35