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NDT Plus Advance Access published online on November 17, 2009

NDT Plus, doi:10.1093/ndtplus/sfp162
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© The Author 2009. Published by Oxford University Press [on behalf of ERA-EDTA]. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Minimal change disease with interferon-beta therapy for relapsing remitting multiple sclerosis

Ananthakrishnapuram Aravindan1, Jim Yong2, Murray Killingsworth2, Michael Suranyi1 and Jeffrey Wong1

1 Department of Nephrology, Liverpool Hospital
2 Department of Anatomical Pathology, Liverpool Hospital, Liverpool, NSW, Australia 2170

Correspondence: A. N. Aravindan; E-mail: aravindanan{at}gmail.com


   Abstract

Interferon beta is widely used for the treatment of relapsing and remitting multiple sclerosis. Renal side effects including nephrotic syndrome have been increasingly described with interferon beta treatment. We describe an illustrative case of a patient who developed severe nephrotic syndrome due to minimal change disease in association with interferon beta therapy and showed partial remission following cessation of interferon beta and treatment with cortico- steroids.

Key Words: interferon beta • minimal change disease • nephrotic syndrome • relapsing remitting multiple sclerosis

Received for publication October 11, 2009. Accepted for publication October 13, 2009.


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