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NDT Plus Advance Access published online on September 23, 2009
NDT Plus, doi:10.1093/ndtplus/sfp137
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© The Author 2009. Published by Oxford University Press [on behalf of ERA-EDTA]. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

The effect of spontaneous twin pregnancy on renal transplant function and haemodynamics

Chee Kay Cheung and Sunil Bhandari

Department of Renal Medicine, Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School, East Yorkshire, HU3 2JZ, UK

Correspondence: Sunil Bhandari; E-mail: sunil.bhandari{at}hey.nhs.uk


  Abstract

Spontaneous twin pregnancy is rare in renal transplant recipients, and confers a significant risk, in terms of both transplant dysfunction and fetal complications. Physiological changes in renal haemodynamics may assist in predicting a favourable outcome, but have not been previously reported in these circumstances. We present a case of a successful outcome for both mother and babies, and detail the effects of the pregnancy on transplant function and haemodynamics within the transplant kidney. Without beneficial circumstances, twin pregnancy may be a high risk in renal transplant recipients and may lead to a poor outcome for both transplant and fetuses.

Key Words: haemodynamics • pregnancy • renal transplantation • twins

Received for publication March 26, 2009. Accepted for publication August 28, 2009.


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