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NDT Plus Advance Access published online on April 28, 2009
NDT Plus, doi:10.1093/ndtplus/sfp044
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© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Clinical management of disturbances of calcium and phosphate metabolism in dialysis patients

Helen Eddington1 and James G. Heaf2

1 Salford Royal NHS Foundation Trust, Manchester, UK
2 Department of Nephrology B, Herlev Hospital, University of Copenhagen, Denmark

Correspondence: Helen Eddington; E-mail: heddington{at}doctors.org.uk


  Abstract

Management of chronic kidney disease–mineral bone disorder can be difficult in renal patients. This review aims to explain why the control of disturbed calcium, phosphate, parathyroid hormone and vitamin D metabolism is important in dialysis patients. The methods available to regulate these parameters include diet, phosphate binders, dialysate calcium, native vitamin D, active vitamin D derivatives and calcimimetics. An overview of current treatment guidelines will be discussed.

Key Words: calcium • phosphate • PTH • uraemia • vitamin D

Received for publication February 19, 2009. Accepted for publication April 3, 2009.


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