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NDT Plus Advance Access originally published online on July 22, 2009
NDT Plus 2009 2(5):387-389; doi:10.1093/ndtplus/sfp093
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© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Symptomatic uraemia from bilateral obstructive uropathy secondary to metastatic urinary bladder cancer showing only unilateral hydronephrosis: a case report

Macaulay A. C. Onuigbo1,2,3

1 College of Medicine, Mayo Clinic, Rochester, MN
2 Department of Nephrology, Midelfort Clinic, Mayo Health System, 1221 Whipple Street, Eau Claire
3 Mayo Health System Practice-Based Research Network (MHS PBRN), Mayo Clinic, Rochester, MN, WI 54702, USA

Correspondence: Correspondence and offprint requests to: Macaulay A. C. Onuigbo; E-mail: onuigbo.macaulay{at}mayo.edu


   Abstract

Bilateral hydronephrosis is classic for supravesical obstructive uropathy causing uraemia with dual functioning kidneys. Recently, a patient presented with uraemia and metastatic urinary bladder carcinoma but only unilateral right-sided hydronephrosis. A right ureteral stent was placed retrograde and no further intervention was planned since the left kidney appeared normal, and since the left ureteric orifice was not visualized. We insisted on a left percutaneous nephrostomy which was successful with prompt urine return. A left nephrostogram revealed unrecognized hydroureter/hydronephrosis. Following haemodialysis, kidney function normalized at 3 weeks. For symptomatic uraemia from obstruction, an antegrade and/or a retrograde decompression must be attempted bilaterally to improve renal salvage.

Key Words: metastatic urinary bladder cancer • nondilated obstructive uropathy • unilateral hydronephrosis • uraemia

Received for publication June 25, 2009. Accepted for publication June 30, 2009.


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