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NDT Plus Advance Access originally published online on July 17, 2009
NDT Plus 2009 2(5):370-372; doi:10.1093/ndtplus/sfp090
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© The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Kikuchi disease preceding systemic lupus erythematosus with membranous lupus nephritis

Arvind Ponnusamy1, Alexander Woywodt2, Roy Reeve3, Jyothi Kondlapudi2 and David Lewis1

1 Renal Department, Salford Royal NHS Foundation Trust, Salford
2 Renal Unit, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire
3 Department of Pathology, Salford Royal NHS Foundation Trust, Salford, UK

Correspondence: Correspondence and offprint requests to: Alexander Woywodt; E-mail: Alex.Woywodt{at}lthtr.nhs.uk


  Abstract

Kikuchi disease (KD) is a rare form of necrotizing lymphadenitis. KD usually presents with cervical lymphadenopathy and fever in young women. It tends to run a benign course and resolve spontaneously within months. The aetiology of the disease is still unclear although a variety of infectious agents have been postulated. There is also a documented but rare association with systemic lupus erythematosus (SLE). We present the case of a young woman with biopsy-proven KD who subsequently developed SLE with biopsy-proven lupus nephritis. Nephrologists should be aware of KD as it may precede the development of SLE and lupus nephritis.

Key Words: Kikuchi disease • lupus nephritis • systemic lupus erythematosus

Received for publication June 19, 2009. Accepted for publication June 25, 2009.


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